中医药延缓病程让艾滋病患者生活质量高没有耐药问题 日常6种食物有助预防艾滋病 治疗艾滋病到哪一步了？艾滋病经典疗法：“鸡尾酒疗法”

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  • 中医药延缓病程让艾滋病患者生活质量高没有耐药问题 日常6种食物有助预防艾滋病 治疗艾滋病到哪一步了？艾滋病经典疗法：“鸡尾酒疗法”

中医药延缓病程让艾滋病患者生活质量高没有耐药问题 日常6种食物有助预防艾滋病

 
　
　
　
 

 

中医药延缓病程让艾滋病患者生活质量高没有耐药问题 日常6种食物有助预防艾滋病
http://www.sina.com.cn  2010年12月01日12:15  中国中医药报

　
图示∶2010年12月即将出版的《中国特色医疗金鉴》登载的刘君主任及其机构　
　
 

慢性艾滋病早期中医药治疗保障生命论证

　　今天是第23个世界艾滋病日，主题为“普遍可及和人权”，意在强调实现艾滋病预防、治疗、关怀和支持的普遍可及是保护人权的当务之急。艾滋病患者长期饱受“鸡尾酒”疗法副作用的伤害，如何提高其生存质量已成为全世界关注的热点之一，西方医药界已开始将目光投向中医药——

　　本报记者 陈斐然

　　艾滋病的医学全名为“获得性免疫缺陷综合征”，由人类免疫缺陷病毒引起。这种病毒终生传染，能够破坏人体免疫系统，使人丧失抵抗各种疾病的能力。艾滋病病毒的传播途径主要包括血液、母婴遗传和性接触等。目前，艾滋病仍是不治之症。鸡尾酒疗法，即抗逆转录病毒疗法，是目前治疗艾滋病的有效方法之一。

　　在今年10月召开的首届国际中医药防治艾滋病大会中，记者了解到，虽然艾滋病疫苗和有效治疗方法在临床上尚未取得实质性进展，但中医药在调节免疫，改善和减轻患者症状，减少抗病毒药引起的毒副作用，提高患者生活质量方面已做出不同程度的成绩。

　　辨证施治，延缓艾滋病进程

　　专家介绍，人体感染艾滋病病毒后，其主要病理过程是T淋巴细胞免疫系统的受损，尤其是CD4免疫细胞遭到损害，而导致各种机会性感染和肿瘤。依据CD4免疫细胞的数量，艾滋病分为4个时期——急性感染期、无症状HIV感染期、艾滋病前期和艾滋病期。

　　健康人的CD4免疫细胞约为800个/立方毫米。在急性感染期，艾滋病病毒载量急剧上升，CD4免疫细胞数量相应下降。但大多数感染者不经治疗，CD4免疫细胞即可回升至正常或接近正常水平。

　　随后进入无症状感染期，CD4免疫细胞持续缓慢减少。在未经治疗的情况下，无症状期每立方毫米CD4免疫细胞每年下降50~60个。大多数感染者在8~10年后降至200个/立方毫米以下，进入艾滋病前期。考虑到“鸡尾酒”疗法的毒副反应、可能过早产生耐药性、高昂的价格等方面，西医不主张在此期进行治疗。

　　针对这一时期，中医主张发挥“治未病”的优势，辨证施治，采用中医药综合疗法，延缓无症状期艾滋病感染者进入艾滋病期。

　　2004年8月起，国家中医药管理局先后在我国17个省(市)、自治区，对艾滋病患者进行中医药治疗。据调查研究表明，无症状期的中医证型主要以虚证为主，随着病程进展，病情复杂化，发展至艾滋病期以虚证和虚实夹杂证多见，虚证贯彻始终。因此，中医药治疗艾滋病无症状期的思路是虚实并治，补虚为主。

　　在艾滋病前期和艾滋病期，多数中医专家分析认为，艾滋病病毒侵入人体，机体外防御体系对入侵邪毒必进行抵抗，或为邪毒犯表，郁于腠理，表卫失和，出现头痛、发热、乏力、咽痛、全身不适等表现；或邪毒入侵犯肺，出现壮热、咳嗽、咯痰、头身疼痛等表现；或皮毛宣泄失畅，邪毒郁于肌奏，出现颈、腋及枕部淋巴结肿大，或急性多发性神经炎、皮疹、肝脾肿大等。因此中医治疗多以“扶正祛邪”为主，目的是提高免疫功能，控制机会性感染，改善生存质量，使患者带毒生存。

　　整体调治，提高机体免疫力

　　高效抗逆转录病毒疗法(HAART)也被称为“鸡尾酒”疗法，是目前治疗艾滋病公认的有效疗法，即3种或3种以上的抗病毒药物联合使用。该疗法可以减少单一用药产生的抗药性，最大限度地抑制病毒的复制，使被破坏的机体免疫功能部分甚至全部恢复。该疗法把蛋白酶抑制剂与多种抗病毒的药物混合使用，从而使艾滋病得到有效的控制。

　　在发达国家，HAART已广泛应用于临床，并取得了显著疗效，但是长期使用HAART会造成严重的毒副作用，往往令患者无法遵守疗程而停止药物治疗，导致大量耐药毒株出现。由于HAART不能彻底清除HIV病毒，病人需要终生服药。但高昂的费用是普通患者难以承担的，一旦停药病人体内的病毒载量也将急剧反弹。

　　中医药在治疗艾滋病时，注重人体的整体功能的调整。目前已有研究显示，中医药对发热、乏力、气短、咳嗽、腹泻等症状有明显改善，其中以乏力改善最为突出。治疗后，患者体重有不同程度的增加，症状体征改善，部分患者恢复了劳动力，生活质量得到了提高。

　　非药物疗法，改善艾滋病症状

　　广西中医学院附属瑞康医院艾滋病研究中心专家提出，在艾滋病患者的日常饮食中，可以加入一些药食同源的药物，如人参、茯苓、白术、甘草、山药、枸杞、百合等，增强患者体质，激发患者元气。

　　针灸疗法虽然不能治愈艾滋病，但可以改善某些临床症状。以扶正培本、益气活血，兼以清热解毒、祛风散寒为原则的针刺疗法，可明显减轻和改善诸如发热、乏力、纳差、腹泻等症状和体征。灸疗具有温经通络、回阳固脱等作用，对于艾滋病等虚损性疾病有很好的效果。

　　适度的体育锻炼对人体的健康有着至关重要的作用。中医学中一些传统的锻炼方法，如五禽戏、八段锦、太极拳、易筋经等对增强体质，激发人体元气功能也有着积极意义。这些也有助于提升艾滋病患者的身体素质和抵御病毒的能力。
日常6种食物有助预防艾滋病
2010-12-01 12:54     稿源: 中国中医药报 
　　黄豆 黄豆中除含丰富蛋白质以外，还含有丰富的硒，硒这种微量元素能提高人体的抗病能力。黄豆中的大豆皂苷，可抑制艾滋病病毒，病毒即使进入体内，也难以生长繁殖。

　　黄瓜 黄瓜中含有胡萝卜素C，能增强人体免疫功能，具有抗病毒、抗癌作用。黄瓜尾部有一种苦味的化学物质，能把进入体内的艾滋病毒杀死。

　　苦瓜 苦瓜中的苦瓜蛋白，对于进入人体内的艾滋病病毒有强烈的抑制作用，美国科学家曾让50例艾滋病患者大量食用苦瓜或口含苦瓜汁，取得了一定的治疗效果。

　　海带 海带中含碘最多，碘化物能促进炎症渗出物的吸收，对癌症有一定的抑制作用。海带中还有硫酸脂，能够保护人体免疫系统的细胞，不受艾滋病病毒的侵害，从而预防艾滋病。

　　鹅血 鹅血中含有大量的免疫球蛋白，能够增强人体的免疫功能，升高血液中的白细胞，促进淋巴细胞的吞噬功能，对艾滋病病毒有较强的抵抗作用。

　　大蒜 大蒜中含有植物杀菌素，对各种病毒也有灭杀作用。常吃大蒜，还能提高免疫能力，预防各种疾病。据研究，将艾滋病病毒放入大蒜汁中5分钟便全部死亡。所以，平时多吃大蒜，对预防艾滋病具有重要的意义。(慧淙)
Chinese medicine to delay the course of daily high quality of life of AIDS patients with food will help prevent AIDS 6
http://www.sina.com.cn 2010 年 12 月 01 日 12:15 Chinese Medicine News
Today is the first of 23 World AIDS Day, the theme "Universal Access and Human Rights", intended to emphasize the implementation of AIDS prevention, treatment, care and support universal access and the protection of human rights imperative. Long-term suffering from AIDS "cocktail" therapy side effects of the injury, how to improve their quality of life has become a focus of attention of one of the world, the Western medical community has begun to set his sights on Chinese Medicine -

Chen striking reporter

AIDS medicine full-called "acquired immunodeficiency syndrome", caused by the human immunodeficiency virus. Transmission of the virus for life, can destroy the human immune system, people lose the ability to resist various diseases. HIV is mainly transmitted through blood, such as maternal genetic and sexual contact. Currently, AIDS is still incurable disease. Cocktail therapy, ie anti-retroviral therapy, is one of the effective treatment of AIDS.

Held in October this year, the First International Congress on AIDS prevention and treatment of Chinese medicine, the reporter learned that, although effective treatment for AIDS vaccine and has not made substantial clinical progress, but in medicine in the regulation of immunity, improve and alleviate the symptoms and reduce the resistance viral drugs cause side effects, improve patient quality of life has made varying degrees of success.

Syndrome differentiation, delaying the process of AIDS

Experts, the human AIDS virus, the main pathological process of T lymphocytes in the immune system is impaired, particularly impaired CD4 immune cells, resulting in a variety of opportunistic infections and tumors. Based on the number of CD4 immune cells, AIDS is divided into four periods - acute infection, asymptomatic HIV infection, AIDS and pre-AIDS.

Healthy people is about 800 CD4 immune cells / cubic mm. In acute infection, the rapid rise in HIV viral load, CD4 corresponding decline in the number of immune cells. But most of the infected without treatment, CD4 immune cells to rebound to normal or near normal levels.

And then went to asymptomatic infection, CD4 immune cells continued to slowly decrease. In untreated cases, symptoms of immune CD4 cells per cubic millimeter per year decreased by 50 ~ 60. Most infections in the 8 to 10 years down to 200 / cubic millimeter below into the pre-AIDS. Taking into account the "cocktail" therapy side effects, drug resistance may be premature, high prices, etc., Western medicine does not advocate for treatment in this period.

For this period, the Chinese claim to play a "disease" of the advantages, syndrome differentiation, the use of combination therapy of Chinese medicine, anti asymptomatic HIV into AIDS.

August 2004, the State Administration of Traditional Chinese Medicine in China has 17 provinces (municipalities) and autonomous regions, and AIDS patients with Chinese medicine treatment. According to the survey results show that asymptomatic period of deficiency syndromes mainly based, as their illness progresses, the disease complex and development to the actual situation of AIDS and the inclusion of the certificate common deficiency, deficiency syndrome consistent. Therefore, Chinese medicine treatment of AIDS symptoms and the actual situation of the idea is to rule, mainly tonic.

HIV and AIDS in the early period, most Chinese experts believe that the AIDS virus into the human body, the body defense system outside the cult poison will to resist invasion, or committed cult poison the table, in the Cou Li Yu, Wei disharmony table, headache, fever , fatigue, sore throat, general malaise and other performance; or cult poison Fanfei invasion, there strong heat, cough, expectoration, pain in head and body performance; or vent loss of fur Chang, Yu cult poison played in the muscle, there neck, axilla and occipital lymph nodes, or acute multiple neuritis, rash, hepatosplenomegaly and so on. Therefore, Chinese medicine treatment and more to "uphold" the main purpose is to improve immune function, control of opportunistic infections, improved quality of life so the survival of patients infected.

Treating the whole, improve immunity

Highly active antiretroviral therapy (HAART), also known as "cocktail" therapy, is recognized as an effective therapy to treat AIDS, that more than 3 or 3 of antiviral drugs in combination. The therapy can reduce the resistance generated by a single agent, the maximum inhibition of viral replication, the immune function of the damaged part or all of recovery. The protease inhibitor therapy to antiviral drugs with a variety of mixed use, so that effective control of AIDS.

In developed countries, HAART has been widely used in clinical and achieved a significant effect, but long-term use of HAART can cause serious side effects, so patients are often unable to comply with treatment to stop drug treatment, leading to a large number of resistant strains appear. HAART can not completely remove the HIV virus, patients need lifelong medication. But the high cost of the average patient is difficult to bear, and once stopping the body's viral load of patients will also be a sharp rebound.

Chinese medicine in the treatment of AIDS, the focus adjustment of the overall function of the human body. At present, studies have shown that Chinese medicine for fever, fatigue, shortness of breath, cough, diarrhea and other symptoms improved, the most prominent of which fatigue improvement. After treatment, patients have varying degrees of increase in body weight, signs and symptoms improved, some patients resumed labor, quality of life improved.

Non-drug therapy, improve symptoms of HIV

Ruikang Affiliated Hospital of Guangxi Medical Center experts for AIDS Research, AIDS patients in the daily diet, you can add some Medicinal and Edible drugs, such as ginseng, Poria, Atractylodes, Licorice, Chinese yam, wolfberry, lily, etc., enhance the physical fitness of patients stimulate the patients strength.

Acupuncture therapy does not cure AIDS, but can improve some clinical symptoms. Training to righting this, Qi and blood circulation, and to detoxify, comfortable and easy for the principles of acupuncture therapy can significantly reduce and improve, such as fever, fatigue, anorexia, diarrhea and other symptoms and signs. Moxibustion with the temperature by-pass network, back to the sun and other solid role off for wasting diseases such as AIDS, have a good effect.

Moderate physical exercise on human health has a vital role. Some traditional Chinese medicine training methods, such as the five animals, Ba Duan Jin, Tai Chi, Yi Jin Jing, etc. for enhancing physical fitness, stimulate the function of the human body also has a positive vitality. These also help to improve physical fitness and resist the AIDS virus.
6 kinds of foods daily will help prevent AIDS
2010-12-01 12:54 is the source: China Pharmaceutical News
Soy beans, in addition to protein-rich, is also rich in selenium, trace elements selenium that can improve the body's resistance to disease. Soybean saponins in soybean can inhibit HIV, the virus enters the body even if, it is difficult growth and reproduction.

Cucumber cucumber contains carotene C, can enhance immune function, with anti-virus, anti-cancer effect. The tail of a bitter cucumber chemicals into the body can kill the HIV virus.

Bitter gourd bitter gourd bitter gourd in the protein, for the AIDS virus into the human body has a strong inhibitory effect, U.S. scientists gave its large consumption of 50 cases of AIDS or mouth with bitter gourd bitter gourd juice, achieved some therapeutic effect.

Most kelp kelp iodine, iodide can promote the absorption of inflammatory exudate, a certain inhibitory effect on cancer. Kelp also sulfuric acid ester, to protect the human immune system cells, from AIDS viruses to prevent AIDS.

Goose goose blood contains large amounts of immune serum globulin, can enhance the body's immune function, increased blood leukocytes, and promote phagocytosis of lymphocytes, the AIDS virus have a stronger role in the resistance.

Garlic Garlic contains phytoncide, on the role of viruses also kill. Eat garlic, but also improve the immunity against various diseases. According to the research, the AIDS virus into the garlic for 5 minutes then all died. So, usually eat garlic, on the prevention of AIDS is of great significance. (Hui Cong)

研究表明中药治疗艾滋病没有耐药问题
http://www.sina.com.cn  2010年12月01日14:13  中国中医药报
　　本报讯  11月29日，湖南长沙市湘雅二医院承担的国家“十一五”防治艾滋病科技重大专项课题组传来消息，自2009年6月至2010年11月，对近2000名艾滋病人进行了病情观察和相关检查，选择部分病人，开展了规范的中药治疗。接受中医药治疗的艾滋病患者，病情明显缓解，各项实验室指标有所改善，无一人中途停止服药、无一人病情恶化或死亡。

　　当前推广的抗艾滋病病毒治疗部分接受治疗者可能出现病毒耐药，并不得不忍受药物的毒副反应。在上述感染者中使用中医药治疗具有其独特的优势，某些中药提取物及其组分具有增强免疫功能和抑制病毒的作用，并能克服艾滋病的不适症状和抗病毒治疗药物带来的副作用。

　　我国广大患者对中医药较能够接受，依从性好；且中药资源丰富，价低效好，毒副作用小，可长期服用，没有耐药性。(刘少龙 宋利)
The results show that there is no medicine to treat AIDS drug problem
http://www.sina.com.cn 2010 年 12 月 01 日 14:13 Chinese Medicine News
WASHINGTON Nov. 29, Second Xiangya Hospital, Changsha, Hunan, assumed the national "Eleventh Five-Year" AIDS major science and technology research group from the news, from June 2009 to November 2010, to nearly 2,000 AIDS disease who were observed and related inspection, some patients choose to carry out the standard of Chinese medicine treatment. Accept medical treatment of AIDS patients, the condition was alleviated, the laboratory parameters improved, no one way to stop medication, no one disease progression or death.

The current promotion of anti-HIV therapy treatment may occur some viral resistance, and had to endure the side effects of drugs. Infection in the treatment of the use of Chinese medicine has its unique advantages, some of the herbal extracts and its components with enhanced immune function and the role of viral suppression, and overcome the symptoms of AIDS and anti-viral drugs side effects .

The majority of patients of Chinese medicine in China more acceptable and better compliance; and rich in traditional Chinese medicine resources, inefficient price is good, toxic side effects can be long-term use, no drug resistance. (Liushao Long Song Lee)
　
 
 
 
　

［ 作者：佚名    转贴自：本站原创    点击数：197    更新时间：2010-12-1    文章录入：nnb ］

　

治疗艾滋病到哪一步了？艾滋病经典疗法：“鸡尾酒疗法”

 
　
　
　
 
治疗艾滋病到哪一步了？
 
鸡尾酒疗法有用但不能根治疫苗还没用于临床
 
浙江在线健康网 health.zjol.com.cn　 2010年12月01日
　
图示∶2010年12月即将出版的《中国特色医疗金鉴》登载的刘君主任及其机构　
　
 

慢性艾滋病早期中医药治疗保障生命论证
 

　　很多人认为艾滋病是不可战胜的病魔。目前的医学对艾滋病有没有办法？得了艾滋病是不是只能等死？

　　今年下半年，浙医一院成立专门的艾滋病病房，病房能容纳16个艾滋病病人，病房负责人朱彪医师说，从病房的情况看，收治过的艾滋病病人病情都很稳定。“他们可以长期活下来。”朱医师说。

　　医生像调酒师一样配药

　　现在临床治疗艾滋病普遍用的是“鸡尾酒疗法”。在西方，鸡尾酒是指几种酒掺在一起调出不同的酒，“我们医生像调酒师一样，把三四种药掺在一起让病人吃。而每种药的比例不同，起到不同的效果，这就是所谓的鸡尾酒疗法。”朱彪医师说。

　　要解释鸡尾酒疗法，先从艾滋病病毒的发病机制讲起——

　　艾滋病病毒是一种逆转录病毒，在显微镜下看起来是个圆形的小球，表面有两层膜含有两种蛋白，里面是病毒基因。病毒表面的蛋白负责攻破人体细胞，进入细胞，把它的基因刻在细胞上。被感染的细胞又可以释放出一万多个病毒颗粒，去侵犯其他正常的细胞。被感染的细胞免疫力特别低下，容易被病毒、真菌等外来分子打败。

　　所以说，艾滋病本身并没有对人体造成很大的伤害，只是让人体失去正常免疫力。

　　鸡尾酒疗法是由美籍华裔科学家何大一在1996年提出的，最主要的好处是减少病毒复制，帮助恢复病人的免疫功能。

　　鸡尾酒疗法主要有四种药：核苷类药物、非核苷类药物、抗蛋白酶抑制剂和整合酶抑制剂，前两种药让艾滋病病毒不能大量繁殖；抗蛋白酶抑制剂是最早使用的抗艾药物，它能阻断病毒感染新的细胞；最后一种药则让繁殖出来的病毒不能遗传到前辈的特性，变得温和。

　　朱彪医师说，鸡尾酒疗法的有效率非常高，几乎全部的病人都在用，艾滋病病毒数量就会明显下降。但是有个问题——病人必须长期服药，不能彻底治好。而且长期服用会造成病人营养不良、血脂浓度增高、肝肾功能受损等副作用。

　　很多病人担心使用鸡尾酒疗法长期服药费用会很高。其实，这个疗法中的大部分药物都可以向当地疾病预防控制机构部分申请报销。即使药费自理，使用国产药物大概每年5000元，进口药物每年2万-3万元。

　　美国和泰国研制的预防性疫苗有效率在31.2%

　　但医学界对此充满怀疑

　　2008年，法国科学家吕克·蒙塔尼因为在上世纪80年代发现艾滋病病毒而获得诺贝尔医学奖，他当时的获奖感言是，要在4-5年之内找到艾滋病的治疗疫苗。而医学界普遍认为如果研制出这个疫苗，那又要拿诺贝尔奖了。

　　治疗疫苗和我们平常所说的疫苗不一样。比如说普通的甲流疫苗，我们接种疫苗就不会得甲型流感，这是起到预防作用疫苗。而艾滋病治疗疫苗，能控制感染者体内的艾滋病病毒，使他们即使有病毒也不发作而影响免疫功能，也不会把病毒传染给其他人。

　　去年的今天，中国科技部宣布，中国科学家李太生研制出艾滋病治疗疫苗，经过为期一年的治疗和随访，患者病毒量下降明显，58.8%的患者血浆中的病毒被抑制到测不出水平，和欧美国家同类研究中这一比例相近。中国有了自己的治疗疫苗，但是还没有投入临床应用。

　　而前年，人类似乎找到了这种艾滋病的预防疫苗。

　　2009年9月24日，美国和泰国研究人员共同宣布，双方合作开发试验的一种“联合疫苗”可以将人体感染艾滋病病毒的风险降低31.2%。这是人类首次获得具有一定免疫效果的艾滋病疫苗。

　　“联合疫苗”试验始于2003年10月，试验对象是在泰国选取的1.6万多名年龄在18岁至30岁的志愿者，是迄今最大规模的艾滋病疫苗试验。志愿者在开始试验时均未感染艾滋病病毒，且其感染风险与普通人群的平均水平相当，其中一组志愿者被注射了“联合疫苗”，另一对照组没有接种。

　　结果显示，在8197名接受疫苗注射的志愿者中，51人感染了艾滋病病毒，而在对照组8198人中，有74人感染，即注射疫苗组感染风险降低了31.2%。

　　在此之前，没有任何一种疫苗能取得这样的免疫效果。但医学界仍然对“联合疫苗”充满怀疑，美国曾有几十种疫苗做临床试验，往往都是当时做了实验有效，过一段时间后又失效了。

　　同是2008年诺贝尔医学奖得主的戴维·巴尔认为，艾滋病变异很快，速度远远超过医学界研究新疫苗的速度，就是说，当疫苗研制出来，病毒老早变了，所以不可能有效。

　　同样，这种预防性疫苗也没有投入临床应用。

来源： 杭州网-都市快报 作者： 王真 编辑： 周莎莎

艾滋病经典疗法：“鸡尾酒疗法”

 

大洋新闻 时间: 2010-12-01 来源: 老人报

 

　　鸡尾酒疗法，原指“高效抗逆转录病毒治疗”，由美籍华裔科学家何大一于1996年提出，是通过三种或三种以上的抗病毒药物联合使用来治疗艾滋病。该疗法的应用可以减少单一用药产生的抗药性，最大限度地抑制病毒的复制，使被破坏的机体免疫功能部分甚至全部恢复，从而延缓病程进展，延长患者生命，提高生活质量。

　　该疗法把蛋白酶抑制剂与多种抗病毒的药物混合使用，从而使艾滋病得到有效的控制。越来越多的科学家相信，混合药物疗法是对付艾滋病的最有效治疗方法，既可以阻止艾滋病病毒繁殖，又可以防止体内产生抗药性的病毒。近年来在其他疾病上，也有人将类似的联合用药疗法称为相对应的“鸡尾酒疗法”。

　　但是鸡尾酒疗法也有一定的局限性，它对早期艾滋病病人相当有效，但对中晚期患者的帮助不大，此疗法的花费也甚高，并非一般人所能承受。     

Where one step treatment of AIDS?
Cocktail therapy useful but no cure yet for clinical vaccine
Zhejiang Online Health Network health.zjol.com.cn 2010 年 12 月 01 日
Many people think that AIDS is a disease of invincibility. Currently there are no medical means of AIDS? AIDS is not only had to die?

Later this year, Zhejiang Medical Institute established a specialized AIDS ward, ward can accommodate 16 AIDS patients, ward leader, said Dr Zhu Biao, from the ward's situation, had treated AIDS patients are stable condition. "They can survive long term." Dr Zhu said.

The same as the bartender dispensing doctors

Now widely used in clinical treatment of AIDS is the "cocktail therapy." In the West, wine cocktail is mixed with the transfer of several different wines, "we as doctors, like bartenders, mixed together, the three or four drugs for patients to eat. The proportion of each drug is different from play different effect, which is called the cocktail therapy. "Zhu Biao, MD, said.

To explain the cocktail therapy, starting with the talk in the pathogenesis of HIV -

HIV is a retrovirus, under the microscope looks like a round ball, the surface of two proteins containing two layers of membrane, which is a viral gene. Virus surface protein responsible for the break human cells into the cell, the genes it engraved cells. Infected cells and can release more than ten thousand virus particles, to infringe upon other normal cells. Special immunity of infected cells is low, easy to viruses, fungi and other foreign elements defeated.

So, AIDS itself does not cause great harm to the human body, just let the body loss of normal immunity.

HAART is a Chinese-American scientists in 1996, David Ho, the main benefit is to reduce viral replication, helping to restore the patient's immune function.

There are four main drug HAART: nucleoside drugs, non-nucleoside drugs, anti-protease inhibitors and integrase inhibitors, the first two drugs for AIDS virus can not multiply; anti-protease inhibitor is the first material used Kangai Yao , can block infection of new cells; final drug is to breed out the virus can not inherit the characteristics of their predecessors, becoming moderate.

Zhu Biao, the doctor said effective HAART is very high, almost all of the patients are in use, HIV viral load will be significantly decreased. But there is a problem - the patient must be long-term medication, can not be completely cured. And long-term use can cause malnutrition patients, blood lipid concentration, side effects such as liver and kidney dysfunction.

Many patients worry about the long-term use of HAART drug costs will be high. In fact, most drugs in this therapy can be to the local disease prevention and control some of the applications for reimbursement. Even if the drugs themselves, the use of domestically produced drugs about 5,000 yuan per year, imports 2 million -3 million per year of drug.

The United States and Thailand have developed a preventive vaccine efficiency of 31.2%

But the medical profession is full of doubt

In 2008, French scientist Luc Montagnier for 80 years in the last century the discovery of AIDS virus awarded the Nobel Prize in Medicine, he was the acceptance speech is to be found in the 4-5 years of treatment of AIDS vaccine. The medical profession generally believe that if the vaccine developed that sought again to take the Nobel Prize.

Therapeutic vaccine and the vaccine we usually do not say the same. For example, a common vaccine, we would not have influenza vaccination influenza vaccine is a preventive role. The AIDS treatment vaccine, the body can control HIV infection so that they do not attack even if the virus affects the immune function, nor will transmit the virus to others.

Day last year, the Chinese Ministry of Science announced that Chinese scientists have developed a Li Taisheng AIDS treatment vaccine, after a period of one year of treatment and follow-up, significantly decreased viral load in patients, 58.8% of patients suppressed the virus in plasma to undetectable levels, and similar studies in Europe and the United States this proportion is similar. China has its own therapeutic vaccine, but have not put into clinical application.

The year before last, we seem to find this kind of AIDS vaccine.

September 24, 2009, joint U.S. and Thai researchers announced that they develop a test "combination vaccine" may be the body reduce the risk of HIV infection 31.2%. This is the first time with a certain human immune effects of AIDS vaccine.

"Combined vaccine" trial began in October 2003, the trials were selected in Thailand more than 1.6 million aged 18 to 30-year-old volunteer, is by far the largest AIDS vaccine trials. Test volunteers were not at the beginning of HIV infection, and the risk of infection and the average level of the general population rather, one group of volunteers have been injected with the "combined vaccine" and the other control group were not vaccinated.

The results showed that the vaccine in the 8197 volunteers, 51 people infected with HIV, 8198 people in the control group, 74 people infected, the vaccinated group 31.2% lower risk of infection.

Prior to this, there is no such a vaccine can be made immune effects. But the medical profession is still on the "combined vaccine" is full of doubt, the United States there have been dozens of clinical trials of vaccines are often effective at doing the experiment, over a period of time and then ineffective.

With the 2008 Nobel Prize winner David Baltimore that the variation of AIDS quickly, much faster than the medical profession of the rate of new vaccines, that is, when the vaccines have been developed, the virus long ago have changed, it is not possible effective.

Again, this is no preventive vaccine into clinical application.

Source: Hangzhou Network - Metro Express of: Wang Zhen Editor: Zhou Shasha
Classic treatment of AIDS: "cocktail therapy"

Ocean News Time: 2010-12-01 Source: old newspaper

Cocktail therapy, originally referred to the "highly active antiretroviral therapy", by the American scientist David Ho in 1996, is by three or more of the combined use of antiviral drugs to treat AIDS. The application of the therapy can reduce the production of single drug resistance, the maximum inhibition of viral replication, so that the damaged part or all of the immune function recovery, thereby delaying disease progression and prolong life, improve the quality of life.

The protease inhibitor therapy to antiviral drugs with a variety of mixed use, so that effective control of AIDS. More and more scientists believe that combination of drugs to combat AIDS therapy is the most effective treatment methods, both to stop HIV reproduction, and can prevent the body resistance of the virus. Other diseases in recent years, someone will have a similar combination therapy as corresponding to the "cocktail therapy."

But the cocktail therapy also has some limitations, its quite effective early AIDS patients, but little help in patients with advanced, the cost of this therapy is also very high, not ordinary people can afford.

　
 
 
 
　

［ 作者：佚名    转贴自：本站原创    点击数：197    更新时间：2010-12-1    文章录入：nnb ］