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南开校长饶子和：变种SARS病毒可能会卷土重来
2009年03月29日 01:30 来源：中国新闻网
3月9日，人民全国人大代表、中国科学院院士、南开大学校长饶子和。 中新社发 金立冬 摄
中新社昆明三月二十八日电 (史广林)“虽然我们抵御了二00三年的SARS，但是变种的SARS可能还会卷土重来，而且毒力更强。”中国科学院院士、南开大学校长饶子和今日在此间举行的科学大讲坛上如是表示。
当日，饶子和主讲了“生命之美-仪态万方的蛋白质精细结构”专题讲座。他首先追忆了西南联大：“云南在南开的历史上有重要的一页，没有云南就没有今天的南开，云南的山水养活了南开，感谢云南父老。”之后九十分钟的演讲中，从SARS到禽流感、从治学到教育改革，饶子和用诙谐幽默的语言深入浅出解释着一个个科学问题，全场听众用多达二十多次的鼓掌表达心中的共鸣。
对于二00三年引起恐慌的SARS病毒，饶子和重申与SARS病毒相关的疾病可能再次爆发，截至目前，他和他的同事仍在深入研究SARS病毒。二00三年SARS爆发期间，饶子和带领团队成功地解析出第一个SARS冠状病毒中的第一个晶体学结构，为抗SARS药物的研制奠定了重要的基础，并因此获得第三世界科学院最高奖——的里雅斯特科学奖。
在演讲最后，饶子和勉励莘莘学子，不论从事什么职业都应当坚持，不要轻言放弃。
饶子和是分子生物物理与结构生物学家，中国科学院院士，第三世界科学院院士，现任南开大学校长。其研究组在世界上首次提出HIV及其家族分子的装配模型，已经系统地表达出二百余个与人类健康密切相关的重要蛋白质，解析出五十多个重要蛋白质的结构。 (完)
“云南中草药可对抗SARS病毒”http://www.shxb.net [2009-3-28 9:59:46] 生活新报网
饶子和简介
饶子和主要从事与重要病毒和肿瘤相关的蛋白质结构、功能以及创新药物的研究。历任牛津大学分子生物物理实验室研究员、清华大学“蛋白质科学”教育部重点实验室主任、生命科学与医学研究院副院长，现为南开大学校长。2003年，饶子和被评为中国科学院院士并任中国科学院生物物理研究所所长。2003年SARS暴发期间，饶子和带领团队成功地解析出第一个SARS冠状病毒中的第一个晶体学结构，为抗SARS药物的研制奠定了重要的基础，并因此获得第三世界科学院最高奖——第里雅斯特科学奖。
来昆参加“科学大讲坛”的南开大学校长饶子和在接受本报专访时称
“我们是应该消灭病毒？还是与病毒和平共处？我觉得后者更符合自然发展规律。”昨日，曾为抗SARS药物的研制奠定了重要基础的著名生物物理与结构生物学家、南开大学校长饶子和接受了本报专访，今日，他将在“科学大讲坛”主讲。他说，云南的一批中草药已经被用于对抗SARS病毒，而且对病毒产生了抑制作用。
“现在如果SARS再来的话，我们应该不会那么害怕了。”饶子和说，现在对SARS病毒的研究已经有了突破性的进展。饶子和透露，在这些研究中，云南的一批中草药被广泛运用。“这些中草药有抑制SARS病毒的功能，现在对SARS患者进行治疗，不会再用激素了。”饶子和说。
饶子和经常挂在嘴边的一句话是“我爱科学，但科学不爱我”。1989年，饶子和在牛津大学读书的时候，开始接触流感蛋白质。“那个项目我做了两年后就开始发毛了，一点头绪都没有。我开始有些丧气，但后来一想，剑桥、哈佛等大学也都没有做出来，我并不能算是笨蛋。”饶子和说，但后来这个项目却被哈佛的一个华裔教授破解了，他对此感到很遗憾。
后来，饶子和开始做艾滋病病毒的研究。在1995年到1996年，一年之内，他分别在《自然》和《细胞》上发表了很有影响的论文。《自然》杂志称他的“艾滋病病毒及其病毒家族分子的装配模型”研究，“为抗AIDS病研究开辟了一条新的途径”。而在2005年，他的研究组在美国《细胞》杂志上发表了世界上首次解析的第一个线粒体膜蛋白复合物II的三维结构，他也因此赢得了2006年度陈嘉庚科学奖。
一般人对各种病毒避之不及，但饶子和却长期与各种病毒“打交道”。“我常常在想，是应该消灭病毒？还是与病毒和平共处？我觉得后者更符合自然发展规律。”饶子和说。
■花 絮
“昆明对南开有恩”
作为南开大学的校长，饶子和说他对昆明有一种特殊的感情。“南开最艰难的时候，在昆明呆了8年，是昆明的水土养育了南开，昆明对南开有恩。”饶子和说。当被问及会不会因此在招生时多给云南一些指标时，饶子和没有直接回答，而是表示很喜欢云南的学生。而当被问及工科学生应该如何选择学校的时候，饶子和表示，工科专业学校有其优点，但也有缺点。他推荐学生到南开上学，自嘲这是在为南开做广告：“屁股决定脑袋。”饶子和爽朗地笑了。本报记者 李冬 实习生 姚宇
南开大学校长饶子和：云南中草药可抗SARS(图)
2009年03月28日 17时03分00秒 来源：都市时报
南开大学校长、著名分子生物物理与结构生物学家饶子和 资料图片
人物简介
饶子和
我国当代著名的分子生物物理与结构生物学家，主要从事与重要病毒和肿瘤相关的蛋白质结构、功能以及创新药物的研究。
历任牛津大学分子生物物理实验室研究员、清华大学“蛋白质科学”教育部重点实验室主任、生命科学与医学研究院副院长。现任南开大学校长。2003年，饶子和被评为中国科学院院士并任中国科学院生物物理研究所所长。
2003年SARS爆发期间，饶子和带领研究团队成功地解析出第一个SARS病毒的蛋白质及其与抑制剂复合物的晶体结构，为抗SARS药物的发现奠定了重要的结构基础，并因此获得第三世界科学院最高奖——“的里雅斯特科学奖”。
今天上午，南开大学校长、著名分子生物物理与结构生物学家饶子和，将在科学大讲坛作专题演讲：“生命之美——仪态万方的蛋白质结构”。昨天，他在接受记者集体采访时表示，南开是一所人文气氛浓郁的综合大学，欢迎云南学子到南开感受人文氛围和科学精神。
南开每年只招3000名本科生
饶子和以科研成名后，才当上南开的校长，他更看重自己的哪个身份呢？
“我首先是南开大学校长，这是我现在的主要工作；业余时间则用来继续我的科研。”“我是第六届中国科协的常委、全国人大代表、国家重大技术研究计划973专家组成员，也是蛋白质、纳米、生殖与发育研究等4个研究所专家组成员。”
作为校长，饶子和亲自给本科生上课。但他一再申明，最先给本科生上课的是清华大学的顾秉林校长。“我做得还不够。作为校长，给本科生上课的目的是推动本科教学，引起其他教授的注意，重视本科教学。”
采访中，饶子和主动提起了南开与云南的渊源，并暗示南开有意反哺云南。
当说到南开今年是否会多招云南学生时，一脸和善的他突然狡黠地笑起来：“这个……我要回校商量。当然，云南学生很不错，在各省中成绩很好，很不错。”他话锋一转说，“我特别希望南开招到那些不是死读书的、品学兼优的云南学生。其实一所大学是否适合学生，也要看学生的发展愿望。南开是一所综合类大学，更注重文化氛围，更有人文气息。南开每年只招3000名本科生，从不扩招，目的就是重视本科的教学、实验，重视本科的人文社团等特色建设。”
饶子和坦言：“我有一个梦，可以自主到各个中学招到南开最喜欢的学生。”他认为，如能杜绝不正之风，自主招生当然就是梦想的实现。但毕竟在分数面前人人平等，自主招生又怎么来确保公平、公正呢？“这是一个考验，也是当今中国高校自主招生能否发展的最大的障碍。”
在他的眼中，那些真正品学兼优的学生，可以通过其在中学的成绩反映出来。“中学老师对自己的学生最了解，即使一次高考没考好，但学生的学习是一个过程，是抹杀不了的，这可以通过自主招生来发现。”他很肯定地说，一些具有特殊专长的优秀学生、一些天才，中学老师最能发现。
正在研究云南中草药
饶子和研究生物蛋白结构。他有关艾滋病毒中的蛋白研究和发现，曾是艾滋病毒研究史上一步重要的进展；而他带领的团队还最早发现了SARS病毒中的蛋白酶结构。最近，饶子和正领导团队致力于禽流感病毒中蛋白结构的研究，一旦发现蛋白结构，找到抑制这一蛋白复制的药物，就能抑制病毒的复制。
“现在，艾滋病毒里的每一个蛋白都明确了，但艾滋病毒的疫苗还没有发现，特效治疗药物还没有，这是为什么？我有个观点，和平共处是最好的。道高一尺魔高一丈，病毒总是这样周而复始。因此，艾滋病毒也好，SARS病毒也好，你要来就来吧，只要你害不死人，就能和平共处。”
饶子和透露，当前他们的研究正结合了云南的某种地方中草药。“希望这批药能对抗SARS，让人不死。如果SARS再来，我们也不用那么害怕。”他还笑言，“最近我们正在研究禽流感病毒。我总认为，很多事做多了就有运气。运气其实也就是一种缘分，搞科研要有一种信心，那就是‘我会有这个运气，不轻言放弃’。”记者杨理锐 （都市时报）
Nankai principals and饶子: variant of SARS virus may stage a comeback
At 1:30 on March 29, 2009 Source: China News Net
March 9, the people on behalf of the National People's Congress, Chinese Academy of Sciences, Nankai University and饶子. China Gold Lidongben hair photo
China news agency, Kunming, March 28 (Shi Guanglin) - "While we resisted the 2003's SARS, but SARS variant may make a comeback, but more toxicity." Academician, Chinese Academy of Sciences, Nankai University Rao son and held here today at a forum on science so that large.
On the same day, Speaker饶子and the "beauty of life - the fine structure of the protein仪态万方" seminars. He first recalled the southwest of the UN General Assembly: "At Nankai Yunnan has an important history of the page, there is no no in today's Yunnan Nankai and Yunnan's mountains and rivers to feed the Nankai, Yunnan thank elders." After 90 minutes of his speech, from the SARS to avian flu, from scholarly research to the education reform, and the use of witty humor饶子language in simple terms to explain a scientific problem, with as many as twenty audience applauded several times expressing sympathy.
In 2003 for the SARS virus caused panic, and reiterated饶子virus and SARS-related diseases may break out again, as of now, he and his colleagues are still in-depth study of the SARS virus. SARS outbreak in 2003, the饶子and successfully led the team to resolve the first of a SARS-CoV in the first crystal structure study for the development of anti-SARS drugs laid the foundation of the essential and, therefore, access to the highest Third World Academy of Sciences Award - Trieste Science Prize.
Speech at the end,饶子and encouraged students, regardless of what kind of career should insist, not to give up easily.
饶子and molecular biophysics and structural biologists, Chinese Academy of Sciences, the Third World Academy of Sciences, the incumbent president of Nankai University. Their research group in the world on HIV and his family the first time the molecular assembly model, has been systematically expressed more than 200 closely related to human health and the importance of protein, essential to resolve the more than 50 protein structures. (END)
"Yunnan, Chinese herbal medicine to combat SARS virus" http://www.shxb.net [2009-3-28 9:59:46] Living Net Hong Kong Daily News
饶子and brief introduction
饶子and is mainly engaged with the important viruses and tumor-associated protein structure, function and innovative drug research. Former University of Oxford researcher Physics Laboratory of Molecular Biology, Tsinghua University, "Protein Science", director of the Ministry of Education Key Laboratory of Life Science and Medical Research Institute, vice president of Nankai University is now. In 2003,饶子and was named Fellow of the Chinese Academy of Sciences and served as director of the Institute of Biophysics, Chinese Academy of Sciences. During the SARS outbreak in 2003, and led the team饶子the successful resolution of the first SARS-CoV in the first crystal structure study for the development of anti-SARS drugs laid the foundation of the important and has received the highest award the Third World Academy of Sciences -- - the first Trieste Science Prize.
Queensland to take part in "Science forum" of Nankai University and饶子said an interview with this paper
"We should eliminate the virus? Or peaceful coexistence with the virus? I think the latter more in line with the laws of natural development." Yesterday, the anti-SARS drugs has laid an important foundation to develop a well-known bio-physical and structural biologists, Nankai University饶子and accepted an interview with this paper today that he would "Science forum" speaker. He said that Yunnan has been a group of Chinese herbal medicines to combat SARS virus, but also resulted in inhibition of virus.
"Now if the SARS again, we should not be so afraid."饶子and said that research on the SARS virus has been a breakthrough in the progress.饶子and revealed that in these studies, a group of Yunnan Province has been extensive use of Chinese herbal medicine. "These herbs have the function of inhibiting SARS virus, and now the treatment of SARS patients will not use the hormone."饶子and Say.
饶子and are usually attributed to the words "I love science, but science does not love me." In 1989, Oxford University饶子and reading at the time, access to influenza protein start. "Me to do that project for two years after the start发毛, that idea did not. I started some frustration, but want one, Cambridge, Harvard University, etc. are NOT to do it, I should not be regarded as stupid."饶子and Say, but the project was a Chinese professor at the Harvard crack, and he was very sorry about that.
Later,饶子and the AIDS virus begin to do research. 1995 to 1996, one year, he at the "natural" and "cells" made a great impact on the thesis. "Nature" magazine called him the "AIDS virus and the virus family of molecular assembly model of" research, "as the anti-AIDS disease has opened up a new way." In 2005, his research group at the United States "cell" magazine published its first analysis of the world on the first mitochondrial membrane protein complex II of the three-dimensional structure, he also won the 2006 Tan Kah Kee Science Award.
Most people avoid any viruses, but it饶子and virus with a variety of long-term "deal." "I often think, should be the eradication of the virus? Or peaceful coexistence with the virus? I think the latter more in line with the laws of natural development."饶子and Say.
■ Others
"Kunming has on the Nankai TU"
Nankai University, as the principals, and said that he饶子Kunming has a special feeling. "Nankai most difficult time spent in Kunming 8 years, the land and water are brought up in Kunming Nankai, Nankai has ex Kunming on."饶子and Say. When asked would not be when many students at a number of indicators to Yunnan,饶子and there is no direct answer, but said he likes the students in Yunnan. When asked about the Engineering School students how to select the time and express饶子, School of Engineering has its major advantages, but there are also shortcomings. Nankai students to recommend him to school, self Nankai This is advertising for: "decided to head butt."饶子and hearty smile. Yao Yu Li trainee reporter
Nankai University and饶子: Yunnan Chinese herbal medicine can be anti-SARS (map)
At 17:03:00 on March 28, 2009 Source: City Times
Nankai University, a well-known physical and structural molecular biology and information biologists饶子Photos
Profile
饶子and
China's contemporary physics and biology of the molecular structure of biologists, mainly engaged in with the important viruses and tumor-associated protein structure, function and innovative drug research.
Former University of Oxford researcher Physics Laboratory of Molecular Biology, Tsinghua University, "Protein Science", director of the Ministry of Education Key Laboratory of Life Science and Medical Research Institute vice president. The current president of Nankai University. In 2003,饶子and was named Fellow of the Chinese Academy of Sciences and served as director of the Institute of Biophysics, Chinese Academy of Sciences.
During the SARS outbreak in 2003, led the research team饶子and successfully resolve the first of a SARS virus protein and its complex with the inhibitor of crystal structure, for the anti-SARS drug discovery has laid an important foundation of the structure and, therefore, was the first Third World Academy of Sciences, the highest award - "Trieste Science Prize."
This morning, Nankai University, a well-known molecular biologist and Structural Biology Physics饶子and will be a forum for science and great keynote speech: "the beauty of life -仪态万方of protein structure." Yesterday, he told said in an interview that the collective, Nankai are rich atmosphere of a humanistic university, welcomed the students to the Nankai Yunnan Humanities atmosphere and feel the spirit of science.
Nankai recruit only 3,000 undergraduate students
饶子and research to become famous only after the president of Nankai when on his own any more attention to identity?
"I first of all, Nankai University, This is now my main job; spare time is used to continue my research." "I am the sixth of the Standing Committee of the Chinese Association for Science and Technology, the National People's Congress, the National Research Program 973 major technical experts group members as well as proteins, nano-, reproductive and developmental research institute of four members of the Group. "
As principals, give饶子and undergraduate classes in person. But he has repeatedly stated that the first class to undergraduates are Binglin Tsinghua University Vice-Chancellor. "I did not go far enough. As a principal, to the undergraduate class is designed to promote undergraduate teaching, the attention of other professors, emphasis on undergraduate teaching."
During the interview, and take the initiative to bring the饶子Nankai and Yunnan origin, and hinted that the south of Yunnan intends to return.
When it comes to whether it will Nankai many bills this year, students in Yunnan, a look of cunning and good of him to suddenly burst out laughing: "This ... ... I want to go to school to discuss. Of course, very good students in Yunnan, in the provinces in grade very good, very good . "He changed the subject said," I would particularly like to hire those who do not die Nankai reading, and students with good academic performance of Yunnan. In fact, the suitability of a university student, it also depends on the development aspirations of students. Nankai is a General universities, will pay more attention to the cultural atmosphere, more humane atmosphere. Nankai recruit only 3,000 undergraduate students, and never Expansion, the purpose of attaching importance to undergraduate teaching, laboratory work, attention to the human society, such as undergraduate construction characteristics. "
饶子and frankly: "I have a dream, you can hire their own in every school students Nankai favorites." In his view, such as to put an end to unhealthy, self-admission of course, is the realization of dreams. But, after all, everyone is equal before the fraction, and independent students, how to ensure a fair, just so? "This is a test of independent colleges and universities in China today is whether the admission of the biggest obstacles to development."
In his eyes, really good academic performance of students who can score in the school reflected. "Middle school teachers know their students best, even if the first test did not test well, but the students are studying a process, are not denied, it can be to find their own admission." He was sure that some of the special expertise outstanding students, some genius found that most secondary school teachers.
Yunnan is studying Chinese herbal medicine
饶子protein structural biology and research. HIV virus in his research and found that the protein, HIV research has been important progress in the history of step; and he also led the team first discovered the SARS virus in the structure of the protease. Recently,饶子and is leading a team dedicated to the avian flu virus in the study of protein structure, protein structure, once found, to find this protein inhibit replication of the drug, can inhibit virus replication.
"Now, the HIV protein of each in the clear, but HIV vaccine has not yet found that treatment effects have not yet, this is why? I have a opinion, peaceful coexistence is the best. Magic rules high一丈, always virus cycle. Therefore, whether HIV, SARS virus, or you want you come, you harm not die as long as people can be peaceful coexistence. "
饶子and revealed that the current study they are combined with Chinese herbs in Yunnan certain places. "We hope that these drugs can fight against SARS, people die. If SARS again, we need not be so afraid." He also笑言, "We are studying the recent avian influenza virus. I think, a lot of things have to do a lot of luck . is a kind of luck is also缘分, engage in scientific research should have a confidence, that is, 'I have the luck, do not give up'. "rationale journalist Yang Rui (City Times)
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