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美报：早服抗艾滋病药物可降低感染率
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| 2011年05月14日 12:07:31 来源： 新华国际 |
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【美国《洛杉矶时报》5月12日报道】题：艾滋病战斗的突破：新药大大降低病毒传染
美国研究者们今天说，一项被称为艾滋病病毒预防里程碑式突破的新研究表明，让艾滋病病毒呈阳性的病人服用抗艾滋病药物可以把配偶和伴侣感染病毒的几率降低96%。
尽管一些研究以往曾指出，用抗逆转录病毒药物治疗病人可以放慢病毒的传染，但美国国家过敏和传染病研究所公布的新结果是证实这些说法的首个大规模临床试验——而且还表明这种药物的效果出乎意料。
国家过敏和传染病研究所主任安东尼·S·福西在一个新闻发布会上说，这项研究表明，尽早治疗艾滋病感染不仅有利于病人自身的健康，而且“明显有利于大大降低他或她伴侣感染的可能性”。
这个始于2005年4月的临床试验在9个国家13个地点开展。
试验募集了1763对只有一人感染病毒的夫妻。这些感染者包括890名男性和873名女性，97%的夫妻是异性恋。研究开始时，所有感染病人的CD4细胞计数——衡量感染严重程度的指标——都在350至550之间。美国治疗指导曰前建议当CD4细胞计数低于500时就开始抗逆转录病毒治疗，但国际指导一股要求等到低于350时才开始治疗。
一半的夫妻中（随机选取）感染者立即开始接受鸡尾酒药物疗法，另一半拖到病人的CD4细胞计数降到350以下或出现艾滋病并发症后才接受治疗。在研究过程中，所有的试验对象都能得到安全性生活的指导、免费的安全套和性传播疾病的治疗。
研究者，上月检查中期结果时发现了 39人新感染了艾滋病病毒。通过对病毒的基因分析，28人显然是被伴侣感染的，7人是因其他原因感染的，而4人的感染原因尚不明确。
在被伴侣新感染的28人中，27人来自延迟进行抗逆转录病毒治疗的一组。
带领这项研究的北卡罗来纳大学的迈伦·科恩说，“我们非常非常惊讶于”减少的幅度。
初步结果也表明，这对病人自身也有利。研究小组在延迟治疗的一组中发现了17例肺结核病例，而在立即治疗的小组中只有3例。肺结核是艾滋病病毒感染者的主要杀手。
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【法新社巴黎5月12日电】联合国卫生官员与社会活动家今天共同称赞一项全球研究成果。这项研究的结果表明，尽早服用抗艾滋病药物可以大大减少从性伙伴处感染艾滋病病毒的风险。
联合国艾滋病规划署执行主任迈克尔·西迪贝在接受记者采访时说：“这是一个扭转局面的进展。我完全惊呆了。”
西迪贝预计，这些发现将推动对艾滋病防治战略的重新思考。
他说，这就需要尽快治疗感染艾滋病病毒的病人，尤其是高危人群，例如男同性恋者、静脉吸毒者和性工作者。
西迪贝说：“这有多重意义。”他指的是鼓励人们去做艾滋病病毒检测，并加快廉价抗逆转录病毒药物的普及。
世界卫生组织总干事陈冯富珍在一份新闻稿中说：“这项研究的发现将进一步加强和支持世卫组织将于7月份公布的指导建议，帮助感染艾滋病病毒的人保护他们的伴侣。”
【法新社巴黎5月12日电】联合国卫生官员与社会活动家今天共同称赞一项全球研究成果。这项研究的结果表明，尽早服用抗艾滋病药物可以大大减少从性伙伴处感染艾滋病病毒的风险。
联合国艾滋病规划署执行主任迈克尔·西迪贝在接受记者采访时说：“这是一个扭转局面的进展。我完全惊呆了。”
西迪贝预计，这些发现将推动对艾滋病防治战略的重新思考。
他说，这就需要尽快治疗感染艾滋病病毒的病人，尤其是高危人群，例如男同性恋者、静脉吸毒者和性工作者。
西迪贝说：“这有多重意义。”他指的是鼓励人们去做艾滋病病毒检测，并加快廉价抗逆转录病毒药物的普及。
世界卫生组织总干事陈冯富珍在一份新闻稿中说：“这项研究的发现将进一步加强和支持世卫组织将于7月份公布的指导建议，帮助感染艾滋病病毒的人保护他们的伴侣。”
艾滋病不治会早死，早治才康复 艾滋病不治会早死，早治才康复 艾滋病不治会早死，早治才康复 艾滋病不治会早死，早治才康复
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| 图示∶2010年12月即将出版的《中国特色医疗金鉴》登载的刘君主任及其机构 |
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U.S. News: Early anti-AIDS drugs can reduce the infection rate service
May 14 2011 12:07:31 Source: Xinhua International
【"Los Angeles Times" reported on May 12】 Question: Combat HIV breakthrough: new drug significantly reduced virus
U.S. researchers said today that HIV prevention is known as a landmark breakthrough in the new study, so that HIV-positive patients taking anti-AIDS drugs to the spouses and partners reduces the chance of infection 96%.
Although some studies have pointed out previously, treatment with antiretroviral drugs can slow down the virus infection patients, but the United States National Institute of Allergy and Infectious Diseases announced new results are confirmed by these statements of the first large-scale clinical trials - but also show that the unexpected effect of this drug.
National Institute of Allergy and Infectious Diseases Director Anthony Fauci S · said at a news conference, the study showed that early treatment of HIV infection not only beneficial to the patient's own health, but "clearly favor the greatly reduced infection in his or her partner possibility. "
This began in April 2005 clinical trials in 13 locations in 9 countries to carry out.
Raise the 1763 pairs of tests only one infected couples. These infections included 890 men and 873 women, 97% of the couples are heterosexual. Beginning of the study, all infected patients CD4 cell count - an indicator to measure the severity of infection - are between 350-550. Guidance, saying the United States before the proposed treatment when the CD4 cell count below 500, I started antiretroviral treatment, but an international guidance only when asked to wait until less than 350 treatment.
Half of the couples in the (randomly selected) infection cocktail to immediately start receiving drug therapy, the other half onto the patient's CD4 cell count dropped to 350 the following or complications occurred after treatment of AIDS. In the study, all subjects have access to safe sex guide, free condoms and sexually transmitted diseases.
Researchers, check the interim results last month, found 39 newly infected with the AIDS virus. Through genetic analysis of the virus, 28 were apparently infected by a partner, and 7 of infection due to other causes, and 4 causes the infection is not clear.
Was partner in 28 new infections, 27 were from delayed antiretroviral treatment group.
The study led by University of North Carolina Mailunkeen said, "We are very, very surprised," the rate of decrease.
Preliminary results also showed that the patients themselves but also beneficial. Research group in the delayed discovery of a group of 17 patients with pulmonary tuberculosis cases, while in the immediate treatment group, only 3 cases. Tuberculosis is a major HIV killer.
【AFP, Paris, May 12 -】 United Nations health officials and social activists, today praised the results of a global study. The results of this study showed that taking anti-AIDS drugs as early as possible can greatly reduce the infection from sexual partners at risk of HIV.
UNAIDS Executive Director Michael Bay West, said in an interview: "This is a progress to reverse the situation. I completely shocked."
Sidibe is expected that these findings will promote AIDS prevention and control strategy rethink.
He said, which requires the treatment of HIV infection as soon as the patient, especially in high-risk groups such as gay men, intravenous drug users and sex workers.
Sidibe said: "This has multiple significance." He was referring to encourage people to do HIV testing and low-cost antiretroviral drugs to speed up the spread.
World Health Organization Director General Margaret Chan said in a press release: "The findings of the study will further strengthen and support the WHO guidance will be published in July proposed to help people infected with HIV to protect their partners."
【AFP, Paris, May 12 -】 United Nations health officials and social activists, today praised the results of a global study. The results of this study showed that taking anti-AIDS drugs as early as possible can greatly reduce the infection from sexual partners at risk of HIV.
UNAIDS Executive Director Michael Bay West, said in an interview: "This is a progress to reverse the situation. I completely shocked."
Sidibe is expected that these findings will promote AIDS prevention and control strategy rethink.
He said, which requires the treatment of HIV infection as soon as the patient, especially in high-risk groups such as gay men, intravenous drug users and sex workers.
Sidibe said: "This has multiple significance." He was referring to encourage people to do HIV testing and low-cost antiretroviral drugs to speed up the spread.
World Health Organization Director General Margaret Chan said in a press release: "The findings of the study will further strengthen and support the WHO guidance will be published in July proposed to help people infected with HIV to protect their partners."
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