艾滋病早治疗能多活30年以上


艾滋病早治疗能多活30年以上

《长城在线》 2009-7-8 PM 03:12:52

    上海市艾滋病治疗专家组组长、上海市(复旦大学附属)公共卫生临床中心教授卢洪洲指出,目前国内艾滋病诊治工作中面临的最大问题在于HIV感染者未能及早被发现;如果及早开展抗病毒治疗,患者寿命可延长30年以上。

  上海市艾滋病治疗专家组今年首次全体会议在上海市公共卫生临床中心召开。与会专家分析了当前国内艾滋病诊治的现状、面临的困难与挑战,最终达成共识并提出艾滋病防治应注重早发现、早治疗。

  HIV感染者很少早期确诊治疗

  市公共卫生临床中心作为上海市惟一艾滋病定点收治单位,从1992年至今收治来自全国各地的艾滋病患者中,在HIV感染早期被确诊并进行随访和治疗的很少,绝大多数患者是因各种严重的机会感染和机会肿瘤在外院就诊过程中发现其HIV抗体检测阳性才转诊来。

  卢洪洲教授曾收治过一名患者,诊治过程中先后出现12种机会感染和机会肿瘤,发病涉及中枢神经系统、肺部、腹腔脏器、眼部等全身多系统器官,病原包括细菌、病毒、真菌、寄生虫等,为临床诊治带来巨大的挑战。

  晚期确诊时免疫力消失殆尽

  上海市艾滋病治疗专家组组长卢洪洲教授指出,目前国内艾滋病诊治工作中面临的最大问题在于HIV感染者未能及早被发现,从而使得这些“隐形”感染者在进入艾滋病晚期时才被确诊,而此时他们体内中重要的免疫细胞CD4+ T淋巴细胞数每微升血液中已降至几十个甚至是几个(正常值为750±250/微升),人体免疫功能已几乎消失殆尽,因此他们中的大多数都合并有严重的机会感染和肿瘤。

  专家表示,在目前没有疫苗的情况下控制传染源最有效的办法就是对感染者的治疗,而在适当的时机开始抗病毒治疗(“鸡尾酒”疗法)患者寿命可再延长30年以上。

  综合医院也应加强抗艾检测

  上海市艾滋病治疗专家组顾问、上海市疾病预防控制中心康来仪教授分析指出, CD4+T淋巴细胞计数目前仍是判断艾滋病分期、何时开始抗反转录病毒治疗以及治疗效果的重要依据。根据最新的临床研究数据,国际专家已达成共识,建议当患者每微升血液中该细胞计数降至350个时就应该启动抗反转录病毒治疗,而对该细胞计数在351到500个之间的HIV感染者启动抗反转录病毒治疗,其预后以及生活质量等也均有改善。

  据此,上海市艾滋病治疗专家组呼吁,应重视加强艾滋病的早期发现和治疗工作。建议在充分发挥定点医院专业核心作用的同时,综合医院也应积极参与艾滋病的检测、治疗工作。为此应对综合医院感染科、皮肤性病科医师就艾滋病相关知识、诊断方法、最新治疗进展进行培训,并通过网络建设加强艾滋病的监测和防治。
( 稿件来源: 39健康网社区 )( 编辑: 孙向向 )

As early as the treatment of AIDS can live for more than 30 years

"Great Wall Online" 2009-7-8 PM 03:12:52

     AIDS treatment team leader, Shanghai, Shanghai (Fudan University), Professor of Public Health Clinical Center, Hong-Zhou Lu pointed out that the current AIDS diagnosis and treatment of domestic work is the biggest problem facing HIV-infected persons could not be found as early as possible; if the anti-viral treatment as soon as possible to carry out patients may be extended for more than 30 years life expectancy.

Shanghai, the first time AIDS treatment expert group meeting in Shanghai this year, Public Health Clinical Center. The experts analyzed the current status of diagnosis and treatment of domestic AIDS, the difficulties and challenges faced, and ultimately reach a consensus and AIDS prevention should focus on early detection, early treatment.

Few HIV-infected persons diagnosed early treatment

The city of Shanghai Public Health Clinical Center as the only fixed-point hospital AIDS units in 1992 from across the country has treated AIDS patients, in HIV infection was diagnosed early and very few follow-up and treatment, the vast majority of patients is due to the kinds of serious opportunistic infections and the opportunity to tumor outside the course of hospital treatment and found positive for HIV antibody testing before referral to.

Professor Lu Hongzhou a patient has been treated, diagnosis and treatment of the process there have 12 kinds of opportunistic infections and the opportunity to tumor incidence related to the central nervous system, lungs, abdominal viscera, eye, such as multi-body system of organs, including pathogenic bacteria, viruses, fungi , parasites and so on, for clinical diagnosis and treatment of enormous challenges.

The time of diagnosis of advanced lost immunity

Shanghai AIDS treatment team leader Professor Lu Hongzhou pointed out that the current AIDS diagnosis and treatment of domestic work is the biggest problem facing HIV-infected persons could not be found as early as possible in order to make these "invisible" in access to AIDS-infected persons have been diagnosed until late, and At this point an important part of their body's immune cells, CD4 + T lymphocytes in the blood increased slightly the number of each has been reduced to a few dozen or even several (normal to 750 ± 250 / increased slightly), the body's immune function has almost disappeared, So most of them are associated with severe opportunistic infections and tumors.

Experts said that there is no vaccine控制传染源is the most effective way of treatment of infected persons, and at an appropriate time to start anti-retroviral therapy ( "cocktail" therapy) in patients with life may be extended for more than 30 years.

General hospital should also step up anti-AIDS Testing

AIDS treatment expert group of consultants in Shanghai, the Shanghai Municipal Center for Disease Control and Prevention, Culture and Sport to Professor Miriam analysis, CD4 + T lymphocyte count is still in stages of AIDS to determine when to start antiretroviral therapy as well as an important basis for treatment. According to the latest clinical research data, have reached a consensus of international experts, it is recommended when the patients increased slightly each of the blood cell count fell to 350 when it should start anti-retroviral treatment, and the cell count in between 351-500 start of the HIV-infected anti-retroviral treatment, their prognosis and quality of life also showed some improvements.

Accordingly, the Shanghai group of experts called for AIDS treatment, attention should be paid to strengthen the early detection of AIDS and treatment. Recommended that hospitals give full play to the role of the professional core, a general hospital should also be actively involved in AIDS testing, treatment. To this end the integrated hospital infection Branch, Dermatology Physicians for AIDS-related knowledge, diagnostic methods, treatment of up-to-date training, and through network-building to strengthen monitoring and prevention of AIDS.
(Article Source: Community Health Network 39) (edit: Sun to to)
 

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