专家:中医药或可成治疗艾滋病有效新途径 艾滋病感染人数居全国第二 广西首启中医治艾项目
来源:科技日报 2010年08月26日07:48
1981年春天在美国洛杉矶的一家医院收治了一名咳嗽患者,症状非常严重,伴有显著的气急、胸闷、呼吸困难,同时病人咽喉部有严重的霉菌感染。经过多方面的检查,结果难以确诊,对症治疗所用的药物也均无效果,最后,这个病人以死亡而告终。相继又有4个人以同样的症状来这家医院诊治,结果同样被死神夺去了生命。
面对这种从未见过的怪病,诊治医生对每一个病例进行了仔细研究,发现这5个人都是同性恋者,结合检查结果得出的结论是:卡氏肺囊虫肺炎。同年7月,当地医院又发现有26例同性恋患者被确诊为卡波氏肉瘤。美国疾病控制中心根据新的病例不断上升情况,开展了进一步调查研究,一年后终于发现这些病人有一个共同的特点——都有细胞免疫缺陷,于是,在1982年9月,这种特殊的疾病被美国疾病控制中心定名为“人类获得性免疫缺陷综合征”,即我们现在所说的艾滋病。
艾滋病是一种慢性致死的传染性疾病,由人类免疫缺陷病毒引起,这是一种能攻击人体免疫系统的病毒。它把人体免疫系统中最重要的CD4+T淋巴细胞作为攻击目标,大量吞噬、侵入和破坏这些细胞,从而破坏人的免疫系统,使人体丧失对各种疾病的抵抗能力。艾滋病本身并不会引发任何疾病,因此,艾滋病本身不是一种病,而是一种无法抵抗其他疾病的状态或综合症。人不会死于艾滋病,而是会死于与艾滋病相关的其他疾病。
艾滋病病毒在人体内的潜伏期平均为6—8年。在发展成艾滋病病人以前,人们可以没有任何症状地生活和工作很多年。在此期间,这些病毒感染者同样具有传染性。
根据艾滋病的发病机理进行治疗,除了针对机会性感染的治疗外,一个重要的治疗措施就是抗逆转录病毒治疗。尽管这种治疗尚不能彻底杀灭病毒,但它的目标是最大限度地抑制病毒的复制,保存和恢复免疫功能,降低病死率和HIV相关性疾病的发病率,提高患者的生活质量,减少艾滋病的传播。
但由于长期用药存在药物不良反应,治疗依从性差,以及病毒耐药性和经济负担等原因,抗病毒治疗并非越早开始越好,需在确定其利大于弊的前提下选择治疗时机。
近年来,国内外开始关注中医药治疗艾滋病的研究。大多从两个方面进行探索,一是认为其病因为“瘟疫”、“伏邪”,用清热解毒类中药,试图从此类药物中筛选出具有抗HIV作用的单味或复方中草药;二是认为其病因为“虚劳”,用补益类中药,包括益气养血、补肾温阳等,认为此类中药具有提高细胞免疫功能的作用。以上研究都取得了一定的成果。
目前,我国中医药治疗艾滋病试点项目已经扩大到了19个省(区、市),包括河南、河北、安徽、湖北、广东、北京、江西、湖南、广西、云南、陕西、吉林、黑龙江、四川、重庆、甘肃和新疆等,为近万名艾滋病患者和感染者提供了免费中医药治疗。
大量临床数据分析结果提示:中药对改善艾滋病的症状体征如乏力、腹泻、发热、咳嗽、皮疹等疗效确切,其中以改善乏力、增加体重最为突出;可以明显减少患者的机会性感染的频率,如常见机会性感染如感冒、发热、腹泻、粘膜溃疡等的发生频率明显减低,可以明显改善患者的生存质量;对HAART引起的部分不良反应具有较好的治疗作用。此外,通过这几年的观察,发现患者CD4淋巴细胞变化呈稳定和逐渐上升的态势,部分病例通过长期观察对病毒载量有一定稳定和降低作用。实践表明,中医药治疗艾滋病可以提高其生存质量,延缓病情的进展速度,延长生存期。未来,中医药治疗艾滋病有望成为一种有效的新途径。
(本文作者徐立然系河南中医一附院肺病科主任医师,卫生部有突出贡献中青年专家,全国中西医结合优秀科技工作者,享受国务院政府特殊津贴专家)
艾滋病感染人数居全国第二 广西首启中医治艾项目
2010年08月26日 07:15法制日报
据了解,至今年6月底,广西已经累计报告艾滋病感染者和病人5万多例,死亡1万多例,感染人数居全国第2位。广西中医药管理局党委书记吴胜华说,自2005年起,广西参加了国家中医药治疗艾滋病试点项目,在南宁市第四人民医院、广西龙潭医院等对艾滋病感染者和患者进行中医药救治,至今,先后有600多名艾滋病病毒感染者和患者接受了免费的中医药治疗,其中有些已持续治疗接近5年。
临床治疗结果表明,中医药治疗可以改善艾滋病相关症状,恢复和增加体重,提高或稳定免疫功能,减轻抗病毒药物的毒副作用,提高艾滋病患者的生存质量。
据介绍,除鹿寨县中医院以外,广西中医学院附属瑞康医院、贺州市中医院、贵港市中医院和苍梧县中医院也是首批中医药治疗艾滋病基地建设单位,这些单位将于今年9月底前全部启动该项目。
- 艾滋病早期治疗是康复与延长30~60年生命的保
- 艾滋病免疫重建的重要意义是挽救生命的根本
- 从食品植物研究开发的治疗艾滋病新药三合皂甙
- 康生丹颗粒免疫实验提示符合艾滋病、肿瘤等应
- 鸡尾酒疗法并非万能,抗药性与毒副作用导致联合疗法与中药疗法应用的迫切性
- 康生丹配合西药治疗AIDS总结
- 三合皂甙,康生丹片
- 中药康生丹治愈艾滋病中医论析
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Expert: Chinese medicine or as new and effective way to treat AIDS the number of HIV infections ranks second in Guangxi, the first treatment Ai Kai items
Source: Science and Technology Daily at 07:48 on the August 26, 2010
The spring of 1981 at a hospital in Los Angeles admitted to a cough, symptoms were very severe, associated with significant shortness of breath, chest tightness, shortness of breath, and throat of patients with severe fungal infections. After many checks, the result difficult to diagnosis, symptomatic treatment is also no effect of drug use, and finally, the patient to die in the end. There are four individuals have the same symptoms to diagnosis and treatment of this hospital, the result was the same death took his life.
Never seen the face of this strange disease, medical treatment for each case was carefully examined and found that 5 people are gay, combined with test results concluded that: Pneumocystis carinii pneumonia. In the same year in July, the local hospital has found 26 cases of homosexual patients were diagnosed with Kaposi's sarcoma. Center for Disease Control under the new cases has Shangsheng circumstances, to carry out further Diaochayanjiu Le, finally Faxianzhexie Bing Ren Hou year have one common feature - Du You cellular immune deficiency, Yu Shi, in September 1982, this particular disease by the U.S. Centers for Disease Control named "human acquired immunodeficiency syndrome", which we now call AIDS.
AIDS is a chronic infectious disease deaths, caused by the human immunodeficiency virus, a human immune system to attack the virus. It is the body's immune system, the most important of CD4 + T lymphocytes as targets, a large number of phagocytosis, invasion and destruction of these cells, thereby undermining the person's immune system so that human loss of resistance to various diseases. AIDS itself does not cause any disease, therefore, AIDS itself is not a disease but a state can not resist other diseases or syndrome. People do not die of AIDS, but will die of other diseases associated with AIDS.
HIV in the body of the average incubation period of 6-8 years. Develop into AIDS patients in the past, people can not have any symptoms for many years to live and work. During this period, these viruses infected the same contagious.
According to the pathogenesis of AIDS treatment, in addition to treatment for opportunistic infections, the treatment measure is an important anti-retroviral therapy. Although this treatment is still not completely kill the virus, but its goal is to maximize the inhibition of viral replication, preservation and restoration of immune function, reduce HIV-related mortality and the incidence of diseases and improve the quality of life of patients and reduce AIDS transmission.
However, there is a long-term medication adverse drug reactions, poor treatment compliance, and economic burden of viral resistance and other reasons, the earlier the start of antiviral therapy is not better, be more good than harm in determining their choice of treatment under the premise of time.
In recent years, started to pay attention at home and abroad of Chinese medicine to treat AIDS. Most exploration in two ways, first, that the disease because of the "plague", "Lingering Evil", with traditional Chinese medicinal, attempts to screen these drugs have anti-HIV effect of the single Chinese or Chinese herbal compound; Second, that the disease because the "consumptive" use the beneficial traditional Chinese medicines, including BNI, kidney yang, etc., that such a medicine could improve immune function. These studies have achieved certain results.
At present, Chinese medicine treatment of AIDS pilot project has been expanded to 19 provinces (autonomous regions and municipalities), including Henan, Hebei, Anhui, Hubei, Guangdong, Beijing, Jiangxi, Hunan, Guangxi, Yunnan, Shaanxi, Jilin, Heilongjiang, Sichuan, Chongqing, Gansu and Xinjiang, to nearly ten thousand infected with AIDS patients and provided free TCM treatment.
The results suggest that a large number of clinical data analysis: traditional Chinese medicine to improve the signs and symptoms of AIDS, such as fatigue, diarrhea, fever, cough, rash and other effects were positive, in which to improve the fatigue, weight gain is most prominent; patients can significantly reduce the frequency of opportunistic infections, such as common opportunistic infections such as colds, fever, diarrhea, mucosal ulceration significantly reduce the frequency, can significantly improve the quality of life of patients; on the part of the side effects caused by HAART has better therapeutic effect. In addition, through these years of observation, found that patients with changes in CD4 lymphocytes was stable and gradually rising trend, in some cases by long-term observation of the viral load and reduce the role of a certain stability. Practice shows that Chinese medicine to treat AIDS can improve their quality of life, delay the progression rate and prolong survival. The future of Chinese Medicine is expected to be an effective new way.
(The Department of Henan Province Xu Ran, director of pulmonary medicine, MD, First Affiliated Hospital, Ministry of young experts with outstanding contributions, the National Integrative Medicine outstanding scientific and technological workers, enjoy special government allowance for experts)
Number of HIV infections in the nation in the treatment of second-Ai Kai's first Guangxi project
At quarter past seven on August 26, 2010 Legal Daily
It is understood that by the end of June this year, Guangxi has reported cumulative AIDS and patients more than 50,000 cases of death more than 10,000 cases, the number of infections ranks No. 2. Guangxi Traditional Chinese Medicine, said party secretary Wu Shenghua, since 2005, Guangxi participated in the national pilot project of Chinese Medicine, the Fourth People's Hospital in Nanning, Guangxi Longtan hospitals and patients on AIDS treatment in Chinese medicine has , has more than 600 HIV-infected people and patients received free treatment in Chinese medicine, some of which have lasted for treatment of almost 5 years.
Clinical results show that TCM can improve the symptoms of AIDS, rehabilitation and weight gain, increase or stabilize the immune system, reduce side effects of antiviral drugs to improve the quality of life of AIDS patients.
According to reports, in addition to other Chinese medicine hospital Luzhai County, Guangxi Medical College Ruikang Hospital, Hezhou hospitals of Chinese medicine and Chinese medicine hospitals Guigang Cangwu County Chinese Medicine Hospital of Chinese Medicine is the first base construction units will be 9 this year All start before the end of the project.
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