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首个有效艾滋病疫苗有望诞生
2010年07月11日09:55 来源：中国日报网站
据英国《每日邮报》7月9日报道，以美国国家过敏及传染病研究学院（NIAID）为首的科研团队近期发现了能抑制91%艾滋病病毒的超级抗体，科学家们因此称有望生产出首个有效的艾滋病疫苗。该研究成果9日被刊登在《科学》杂志上。
有些人染上艾滋病病毒后体内能产生强大的免疫系统蛋白，帮助他们延长生命。人体内出现能抑制几个艾滋病病毒菌株的抗体并不罕见，然而，直到去年科学家才找到一些能中和大量艾滋病病株的抗体，不过，没有一种抗体能抑制超过40%的菌株。
纳贝尔（Nabel）领导的这个科研团队此次发现的超级抗体是利用自制的设备在一个艾滋病病毒携带者身上发现的，正是这两种自然产生被称为VRC01和VRC02的抗体让此人免于疾病侵袭。
艾滋病病毒很难消灭的一个原因是它会不断的发生变异，人的免疫系统和药物只能很被动的去追这个游离不定的目标。研究团队成员马克斯利表示：“这两种抗体依附在艾滋病病毒不会发生变异的部位，这就是为什么它们能中和如此大量艾滋病病毒菌株的原因。”
此前，生产艾滋病疫苗几乎是个不可完成的任务。去年9月，研究人员称在泰国进行的一个艾滋病疫苗测验显示，该疫苗可以降低30%的感染率，但有分析人士称这个结果没有统计显著性。
据悉，艾滋病病毒通常会发展成为艾滋病，英国约有7.3万艾滋病病毒携带者，专家们认为有30%的携带者都不知道自己已被感染。自上世纪80年代初艾滋病开始大流行以来，全球已经有3300万人患上此病，2500万人因此死亡。科学家纳贝尔表示：“与过去10年相比，我现在对艾滋病疫苗的出现更为乐观了。”(蔡东海)
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The first birth of an effective AIDS vaccine is expected to
At 09:55 on the July 11, 2010 Source: China Daily Website
According to the British "Daily Mail" reported on July 9, to the National Institute of Allergy and Infectious Diseases (NIAID) research team headed by recently discovered the AIDS virus can inhibit 91% of the super-antibody, the scientists expected to produce so called The first effective AIDS vaccine. The research was published in 9 "Science" magazine.
Some people infected with AIDS virus, the body can produce a powerful immune system proteins, helping them to extend their lives. The body appears to inhibit the number of strains of HIV antibodies is not uncommon, however, until last year, scientists could only find some diseased plants in and a large number of HIV antibodies, but not an antibody can inhibit more than 40% of the strains.
Naber (Nabel) led the research team found that super-antibody is the use of home-made device in an HIV carrier was found, and is both naturally occurring and VRC02 called VRC01 antibodies to the human-free in the disease.
HIV is difficult to eliminate one of the reasons is that it constantly mutates human immune system and drugs can only be very passive, chase the goal of this free variable. Research team members Makesili said: "These two antibodies attached to the AIDS virus does not mutate the site, which is why they can and in such a large number of causes of HIV strains."
Previously, the production of AIDS vaccine is almost a mission impossible. Last year in September, the researchers say in Thailand, an AIDS vaccine test revealed that the vaccine can reduce the infection rate of 30%, but analysts say the results are not statistically significant.
It is reported that HIV will usually develop into AIDS, the United Kingdom there are about 73,000 HIV carriers, experts say 30% of the carriers do not know that they have been infected. Since the early 80 century and the beginning of a pandemic of AIDS since the 3300 million people worldwide have contracted the disease, 2,500 people died. Scientists Naber said: "Compared with the past 10 years, I have now the emergence of AIDS vaccine is more optimistic." (Cai Donghai)
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