Blood :干细胞移植手术治愈艾滋病毒感染者的证据


Blood :干细胞移植手术治愈艾滋病毒感染者的证据

 
 
 
 
 
Blood :干细胞移植手术治愈艾滋病毒感染者的证据
    
   
  来源: 生物谷Bioon.com        发布时间:2010-12-15 
 
图示∶2010年12月即将出版的《中国特色医疗金鉴》登载的刘君主任及其机构 
 
 

慢性艾滋病早期中医药治疗保障生命论证

 
    
 

  2007年,柏林一名感染HIV病毒的白血病人接受了干细胞移植手术。医生为他移植了可以抵抗艾滋病毒的干细胞,并借此成功地治愈了他的艾滋病毒感染。负责这一病例的医生们最近证实了这个消息。

  上述案例首次被公之于众是在2008年波士顿举行的逆转录病毒以及机会感染会议上。之后,柏林的医务人员在2009年2月的新英格兰医学杂志(New England Journal of Medicine )上详细地介绍了这个案例。关键在于移植到病人体内的骨髓很特殊---它来自于一个先天对HIV病毒免疫的骨髓捐赠者。先天免疫是因为此人特殊的基因档案(genetic profile)使得它体内不存在艾滋病毒赖以传播的CCR5辅助受体。CCR5是一种趋化因子,在HIV体内传播中它的作用就如同笔记本电脑的“充电基座”,大部分HIV病毒必须附着在它之上才能进入并感染CD4细胞。(CD4 是一种T细胞,HIV病毒感染并破坏它---译者)

  柏林医务人员近日在Blood 杂志上发表了一份后续报告,声称经过细致的检测,“完全有理由确定这一HIV感染病例已被完全治愈。”


* 中国红丝带网资讯类信息均为转载,不代表中国红丝带网立场
Blood: Stem cell transplantation to cure evidence of HIV
     
  
  Source: Bio-Valley Bioon.com :2010-12-15
 


In 2007, one infected with HIV virus in Berlin to accept a leukemia stem cell transplant. As the doctor can transplant the stem cells against HIV, and to successfully cured him of HIV infection. The doctors in charge of the case confirmed the news recently.

The case was first made public in 2008, held in Boston, and opportunistic infections retrovirus conference. After the medical staff in Berlin in February 2009 the New England Journal of Medicine (New England Journal of Medicine) on the detailed description of the case. The key is to transplant into the patient's bone marrow is very special --- it comes from an innate immunity against HIV, bone marrow donor. Innate immunity because the person a special genetic profile (genetic profile) so that it does not exist in vivo which the spread of HIV coreceptor CCR5. CCR5 is a chemokine, in the spread of HIV in the body it acts like a notebook computer, "charging base, " most of the HIV virus must be attached on top of it to enter and infect CD4 cells. (CD4 is a T cell, HIV infection and destroy it --- Translator)

Medical staff in Berlin recently published in the journal Blood a follow-up report, claiming that after careful testing, "have every reason to determine the HIV infection cases have been completely cured. "
 

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[ 作者:佚名    转贴自:本站原创    点击数:196    更新时间:2010-12-16    文章录入:nnb ]