美刊十大医学突破公布 我科学家一成果入选

美刊十大医学突破公布我科学家一成果入选

2009年12月15日 08:43:08 　来源：京华时报

从iPS细胞发育而成的小鼠

近日，美国《时代周刊》公布了今年十大医学突破，中国科学家在2008年利用诱导性多能干细胞培育出的小鼠有幸入选。

这只小鼠名叫“小小”，它的诞生代表了一个重大科学进展。“小小”是中国科学家于2008年11月利用诱导性多能干细胞培育出的。诱导性多能干细胞是通过转入四种基因将来源于成年动物的体细胞重编程后得到的具有胚胎干细胞状态的细胞。这些细胞在培养后能够发育为小鼠，在此研究之前，只有利用胚胎干细胞能够获得这一成果。

中国科学家利用iPS细胞能够得到成活的具有繁殖能力的小鼠，从而在世界上第一次证明了诱导性多能干细胞与胚胎干细胞具有相似的多能性。科学家表示，这一研究成果表明诱导性多能干细胞或许同胚胎干细胞一样可以作为治疗各种疾病的潜在来源。

此项成果在全球引起了强烈的反响，全世界3000多家媒体在第一时间报道了该项研究成果。克隆羊“多莉”的老家、罗斯林研究所发育生物学部主任BruceWhitelaw认为，在克隆的道路上，“‘小小’接过了‘多莉’点燃的火炬”。（记者李铁铮）

·中国科学家首次用iPS细胞克隆出活体小鼠

America Journal to publish my top ten medical breakthroughs scientists, the outcome of a selected
December 15, 2009 08:43:08 Source: Beijing Times



Formed from the iPS cell development in mice

    Recently, the U.S. "Time magazine," announced the top ten medical breakthroughs of this year, Chinese scientists in 2008, the use of induced pluripotent stem cells of mice bred privilege selected.

    Only in mice called "small", which represents the birth of a major scientific advances. "Little" is the Chinese scientists in November 2008 the use of induced pluripotent stem cells cultivated in. Induced pluripotent stem cells through the transfer of four genes from an adult animal somatic cells obtained after re-programming of embryonic stem cells that have the status of cell. These cultured cells can develop into mice, in this study, only the use of embryonic stem cells able to obtain this result.

    Chinese scientists have used iPS cells can be survived with the reproductive capacity of mice, and thus the world's first proof of induced pluripotent stem cells and embryonic stem cells have a similar pluripotency. Scientists said the findings show that induced pluripotent stem cells may be the same as embryonic stem cells can be used as a potential source of treatment of various diseases.

    This results in the global rise to a strong response, more than 3,000 media around the world reported the first results of the study. Cloned sheep "Dolly" the home, the Department of Developmental Biology, Roslin Institute, director of BruceWhitelaw that, in cloning the road, " 'Little' took over 'Dolly' lit the torch." (Xinhua Li Tiezheng)

    * Chinese scientists to use iPS cell clones for the first time in live mice body